Application of Box-Behnken design for optimization of phenolics extraction from Leontodon hispidulus in relation to its antioxidant, anti-inflammatory and cytotoxic activities

Abstract To the best of our knowledge, there have been no phytochemical studies concerning the wild plant Leontodon hispidulus Boiss. (Asteraceae). Optimization of the green extraction process of the plant aerial parts, identification of main phenolic compounds, evaluation of antioxidant, anti-infla...

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Bibliographic Details
Main Authors: Noha Mokhtar Abd-El-Aziz, Mohamed S. Hifnawy, Ahmed A. El-Ashmawy, Rehab A. Lotfy, Inas Y. Younis
Format: Article
Language:English
Published: Nature Portfolio 2022-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-12642-2