Central role of cardiac fibroblasts in myocardial fibrosis of diabetic cardiomyopathy

Central role of cardiac fibroblasts in myocardial fibrosis of diabetic cardiomyopathy

Diabetic cardiomyopathy (DCM), a main cardiovascular complication of diabetes, can eventually develop into heart failure and affect the prognosis of patients. Myocardial fibrosis is the main factor causing ventricular wall stiffness and heart failure in DCM. Early control of myocardial fibrosis in D...

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Bibliographic Details
Main Authors: Yanan Cheng, Yan Wang, Ruili Yin, Yongsong Xu, Lijie Zhang, Yuanyuan Zhang, Longyan Yang, Dong Zhao
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-03-01
Series:Frontiers in Endocrinology
Subjects:
diabetic cardiomyopathy
cardiac fibrosis
cardiac myofibroblasts
cardiac fibroblasts
imbalance of extracellular matrix synthesis and degradation
disorder of matrix metalloproteinases synthesis
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2023.1162754/full

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https://www.frontiersin.org/articles/10.3389/fendo.2023.1162754/full

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