Ruxolitinib for the Treatment of Essential Thrombocythemia

Abstract. Deregulated Janus Kinase 2 (JAK2) activation is central to the pathogenesis of most myeloproliferative neoplasms (MPNs), of which essential thrombocythemia (ET) is the most common entity. Patients with ET are risk-stratified according to their risk of thrombo-hemorrhagic complications. Hig...

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Bibliographic Details
Main Authors: Arief Gunawan, Patrick Harrington, Natalia Garcia-Curto, Donal McLornan, Deepti Radia, Claire Harrison
Format: Article
Language:English
Published: Wiley 2018-08-01
Series:HemaSphere
Online Access:http://journals.lww.com/10.1097/HS9.0000000000000056