Voltage-dependent gating in a "voltage sensor-less" ion channel.

The voltage sensitivity of voltage-gated cation channels is primarily attributed to conformational changes of a four transmembrane segment voltage-sensing domain, conserved across many levels of biological complexity. We have identified a remarkable point mutation that confers significant voltage de...

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Bibliografische gegevens
Hoofdauteurs: Harley T Kurata, Markus Rapedius, Marc J Kleinman, Thomas Baukrowitz, Colin G Nichols
Formaat: Artikel
Taal:English
Gepubliceerd in: Public Library of Science (PLoS) 2010-02-01
Reeks:PLoS Biology
Online toegang:http://europepmc.org/articles/PMC2826373?pdf=render