Alternate atxA and acpA dependent response of Bacillus anthracis to serum, HCO3- and CO2.

Bacillus anthracis overcomes host immune responses by producing capsule and secreting toxins. Production of these virulence factors in response to entering the host environment was shown to be regulated by atxA, the major virulence regulator, known to be activated by HCO3- and CO2. While toxin produ...

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Bibliographic Details
Main Authors: Itai Glinert, Elad Bar-David, Amir Ben-Shmuel, Assa Sittner, Reut Puni, Shira Laredo, David Kobiler, Shay Weiss, Haim Levy
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0281879