Genome-Wide RNA Sequencing of Human Trabecular Meshwork Cells Treated with TGF-β1: Relevance to Pseudoexfoliation Glaucoma

Genome-Wide RNA Sequencing of Human Trabecular Meshwork Cells Treated with TGF-β1: Relevance to Pseudoexfoliation Glaucoma

Pseudoexfoliation glaucoma (XFG) is an aggressive form of secondary open angle glaucoma, characterised by the production of exfoliation material and is estimated to affect 30 million people worldwide. Activation of the TGF-β pathway by TGF-β1 has been implicated in the pathogenesis of pseudoexfoliat...

Full description

Bibliographic Details
Main Authors: Anton W. Roodnat, Breedge Callaghan, Chelsey Doyle, Megan Henry, Katarzyna Goljanek-Whysall, David A. Simpson, Carl Sheridan, Sarah D. Atkinson, Colin E. Willoughby
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Biomolecules
Subjects:
exfoliation syndrome
exfoliation glaucoma
pseudoexfoliation syndrome
pseudoexfoliation glaucoma
open-angle glaucoma
transforming growth factor beta1
Online Access:https://www.mdpi.com/2218-273X/12/11/1693

Internet

https://www.mdpi.com/2218-273X/12/11/1693

Similar Items