A novel dual-color reporter for identifying insulin-producing beta-cells and classifying heterogeneity of insulinoma cell lines.

A novel dual-color reporter for identifying insulin-producing beta-cells and classifying heterogeneity of insulinoma cell lines.

Many research studies use immortalized cell lines as surrogates for primary beta- cells. We describe the production and use of a novel "indirect" dual-fluorescent reporter system that leads to mutually exclusive expression of EGFP in insulin-producing (INS(+)) beta-cells or mCherry in non-...

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Bibliographic Details
Main Authors: Nan Sook Lee, Joyce G Rohan, Madison Zitting, Sonia Kamath, Andrew Weitz, Arnold Sipos, Paul M Salvaterra, Kouichi Hasegawa, Martin Pera, Robert H Chow
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3329476?pdf=render

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http://europepmc.org/articles/PMC3329476?pdf=render

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