Radiolabeling Strategies of Nanobodies for Imaging Applications

Radiolabeling Strategies of Nanobodies for Imaging Applications

Nanobodies are small recombinant antigen-binding fragments derived from camelid heavy-chain only antibodies. Due to their compact structure, pharmacokinetics of nanobodies are favorable compared to full-size antibodies, allowing rapid accumulation to their targets after intravenous administration, w...

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Bibliographic Details
Main Authors: Jim Küppers, Stefan Kürpig, Ralph A. Bundschuh, Markus Essler, Susanne Lütje
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Diagnostics
Subjects:
nanobodies
labeling strategies
positron emission tomography
single photon emission computed tomography
radiometals
radiohalogens
Online Access:https://www.mdpi.com/2075-4418/11/9/1530

Internet

https://www.mdpi.com/2075-4418/11/9/1530

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