Circulatory collapse during wound closure in spine surgery with an unknown cause: a possible adverse effect of topical application of vancomycin?

Abstract Background Vancomycin (VCM) is effective in fighting Gram-positive bacteria related severe infections, and topical application of VCM powder is widely used in orthopedic surgery to prevent wound infection. However, VCM could lead to infusion rate-dependent antibody-and complement-independen...

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Bibliographic Details
Main Authors: Xiaoqing Zhang, Wenwen Zhai, Min Li, Xiangyang Guo
Format: Article
Language:English
Published: BMC 2021-01-01
Series:BMC Anesthesiology
Subjects:
Online Access:https://doi.org/10.1186/s12871-020-01220-6