Ex vivo radiation sensitivity assessment for individual head and neck cancer patients using deep learning-based automated nuclei and DNA damage foci detection

Ex vivo radiation sensitivity assessment for individual head and neck cancer patients using deep learning-based automated nuclei and DNA damage foci detection

Introduction: Tumor biopsy tissue response to ex vivo irradiation is potentially an interesting biomarker for in vivo tumor response, therefore, for treatment personalization. Tumor response ex vivo can be characterized by DNA damage response, expressed by the large-scale presence of DNA damage foci...

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Bibliographic Details
Main Authors: I. Lauwers, K.S. Pachler, M.E. Capala, N.D. Sijtsema, D.C. Van Gent, M. Rovituso, M.S. Hoogeman, G.M. Verduijn, S.F. Petit
Format: Article
Language:English
Published: Elsevier 2024-03-01
Series:Clinical and Translational Radiation Oncology
Online Access:http://www.sciencedirect.com/science/article/pii/S2405630824000120

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http://www.sciencedirect.com/science/article/pii/S2405630824000120

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