Linking Temperature, Cation Concentration and Water Activity for the B to Z Conformational Transition in DNA

High concentrations of Na+ or [Co(NH3)6]3+ can induce the B to Z conformational transition in alternating (dC-dG) oligo and polynucleotides. The use of short DNA oligomers (dC-dG)4 and (dm5C-dG)4 as models can allow a thermodynamic characterization of the transition. Both form right handed double he...

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Bibliographic Details
Main Authors: Jaime M. Ferreira, Richard D. Sheardy
Format: Article
Language:English
Published: MDPI AG 2018-07-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/23/7/1806