Linking Temperature, Cation Concentration and Water Activity for the B to Z Conformational Transition in DNA
High concentrations of Na+ or [Co(NH3)6]3+ can induce the B to Z conformational transition in alternating (dC-dG) oligo and polynucleotides. The use of short DNA oligomers (dC-dG)4 and (dm5C-dG)4 as models can allow a thermodynamic characterization of the transition. Both form right handed double he...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2018-07-01
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Series: | Molecules |
Subjects: | |
Online Access: | http://www.mdpi.com/1420-3049/23/7/1806 |