AMPK β1 reduces tumor progression and improves survival in p53 null mice

AMPK β1 reduces tumor progression and improves survival in p53 null mice

The AMP‐activated protein kinase (AMPK) is a heterotrimeric protein complex that is an important sensor of cellular energy status. Reduced expression of the AMPK β1 isoform has been linked to reduced survival in different cancers, but whether this accelerates tumor progression and the potential mech...

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Bibliographic Details
Main Authors: Vanessa P. Houde, Sara Donzelli, Andrea Sacconi, Sandra Galic, Joanne A. Hammill, Jonathan L. Bramson, Robert A. Foster, Theodoros Tsakiridis, Bruce E. Kemp, Giuseppe Grasso, Giovanni Blandino, Paola Muti, Gregory R. Steinberg
Format: Article
Language:English
Published: Wiley 2017-09-01
Series:Molecular Oncology
Subjects:
ACC
metabolism
cancer
lipogenesis
Online Access:https://doi.org/10.1002/1878-0261.12079

Internet

https://doi.org/10.1002/1878-0261.12079

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