The role of IgE specific for galactose-α-1,3-galactose in predicting cetuximab induced hypersensitivity reaction: a systematic review and a diagnostic meta-analysis

Abstract Recombinant monoclonal antibodies are used for treating various diseases, from asthma, rheumatoid arthritis, and inflammatory bowel disease to cancer. Although monoclonal antibodies are known to have fewer toxic reactions compared with the conventional cytotoxic antineoplastic drugs, the ca...

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Bibliographic Details
Main Authors: Cristian Virgil Lungulescu, Bogdan Silviu Ungureanu, Adina Turcu-Stiolica, Valentina Ghimpau, Stefan Alexandru Artene, Irina Mihaela Cazacu, Alexandru Florian Grecu, Venera Cristina Dinescu, Adina Croitoru, Simona Ruxandra Volovat
Format: Article
Language:English
Published: Nature Portfolio 2020-12-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-020-78497-7