Methylation levels of SLC23A2 and NCOR2 genes correlate with spinal muscular atrophy severity.

Methylation levels of SLC23A2 and NCOR2 genes correlate with spinal muscular atrophy severity.

Spinal muscular atrophy (SMA) is a monogenic neurodegenerative disorder subdivided into four different types. Whole genome methylation analysis revealed 40 CpG sites associated with genes that are significantly differentially methylated between SMA patients and healthy individuals of the same age. T...

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Bibliographic Details
Main Authors: Galina Yu Zheleznyakova, Emil K Nilsson, Anton V Kiselev, Marianna A Maretina, Lyudmila I Tishchenko, Robert Fredriksson, Vladislav S Baranov, Helgi B Schiöth
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0121964

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https://doi.org/10.1371/journal.pone.0121964

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