Molecular dissection of the glutamine synthetase-GlnR nitrogen regulatory circuitry in Gram-positive bacteria
How bacteria sense and respond to nitrogen is a key question in microbial physiology. This work unveils the mechanism by which the central nitrogen metabolic enzyme, glutamine synthetase, directly signals nitrogen availability to the GlnR regulator.
| Main Authors: | , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2022-07-01
|
| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-022-31573-0 |