Molecular dissection of the glutamine synthetase-GlnR nitrogen regulatory circuitry in Gram-positive bacteria

How bacteria sense and respond to nitrogen is a key question in microbial physiology. This work unveils the mechanism by which the central nitrogen metabolic enzyme, glutamine synthetase, directly signals nitrogen availability to the GlnR regulator.

Xehetasun bibliografikoak
Egile Nagusiak: Brady A. Travis, Jared V. Peck, Raul Salinas, Brandon Dopkins, Nicholas Lent, Viet D. Nguyen, Mario J. Borgnia, Richard G. Brennan, Maria A. Schumacher
Formatua: Artikulua
Hizkuntza:English
Argitaratua: Nature Portfolio 2022-07-01
Saila:Nature Communications
Sarrera elektronikoa:https://doi.org/10.1038/s41467-022-31573-0