Association of VDBP rs4701 variant, but not VDR/RXR-α over-expression with bone mineral density in pediatric β-Thalassemia patients

Association of VDBP rs4701 variant, but not VDR/RXR-α over-expression with bone mineral density in pediatric β-Thalassemia patients

Introduction: The reduced rate of bone formation despite the availability of vitamin D has been reported in β-thalassemia.  This suggests genetic factors together with environmental one can be implicated in this condition. Since vitamin D binding protein (VDBP) maintains bioavailability of vitamin D...

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Bibliographic Details
Main Authors: Shaimaa Sahmoud, Mostafa Ibrahim, Eman Toraih, Noha Kamel, Manal Fawzy, Samar Elfiky
Format: Article
Language:English
Published: Mattioli1885 2020-06-01
Series:Mediterranean Journal of Hematology and Infectious Diseases
Subjects:
Bone mineral density; Gene expression; Genotyping; Real-Time PCR; RXRA; Single nucleotide polymorphism; Thalassemia; VDBP; VDR
Online Access:http://mjhid.org/index.php/mjhid/article/view/4214

Internet

http://mjhid.org/index.php/mjhid/article/view/4214

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