Nicotinamide adenine dinucleotide metabolism and arterial stiffness after long-term nicotinamide mononucleotide supplementation: a randomized, double-blind, placebo-controlled trial

Abstract Many animal studies have shown that oral administration of the nicotinamide adenine dinucleotide (NAD+) precursor nicotinamide mononucleotide (NMN) prevents the reduction of NAD+ levels in organs and tissues, helping alleviate aging-related diseases. However, there are very few clinical rep...

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Bibliographic Details
Main Authors: Takeshi Katayoshi, Sachi Uehata, Noe Nakashima, Takahisa Nakajo, Natsuko Kitajima, Masakatsu Kageyama, Kentaro Tsuji-Naito
Format: Article
Language:English
Published: Nature Portfolio 2023-02-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-29787-3