Ambient Benzo[a]pyrene’s Effect on Kinetic Modulation of Amyloid Beta Peptide Aggregation: A Tentative Association between Ultrafine Particulate Matter and Alzheimer’s Disease

Ambient Benzo[a]pyrene’s Effect on Kinetic Modulation of Amyloid Beta Peptide Aggregation: A Tentative Association between Ultrafine Particulate Matter and Alzheimer’s Disease

Long-time exposure to ambient ultrafine particles is associated with an increased risk of neurodegenerative diseases such as Alzheimer’s disease (AD), which is triggered by the aggregation of Aβ peptide monomers into toxic oligomers. Among different ultrafine air pollutants, polycyclic aromatic hydr...

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Bibliographic Details
Main Authors: Samal Kaumbekova, Mehdi Amouei Torkmahalleh, Dhawal Shah
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Toxics
Subjects:
environmental toxicology
benzo[a]pyrene
molecular dynamics simulations
Alzheimer’s disease
amyloid peptide aggregation
oligomerization
Online Access:https://www.mdpi.com/2305-6304/10/12/786

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https://www.mdpi.com/2305-6304/10/12/786

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