A bioactive peptide amidating enzyme is required for ciliogenesis

A bioactive peptide amidating enzyme is required for ciliogenesis

The pathways controlling cilium biogenesis in different cell types have not been fully elucidated. We recently identified peptidylglycine α-amidating monooxygenase (PAM), an enzyme required for generating amidated bioactive signaling peptides, in Chlamydomonas and mammalian cilia. Here, we show that...

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Bibliographic Details
Main Authors: Dhivya Kumar, Daniela Strenkert, Ramila S Patel-King, Michael T Leonard, Sabeeha S Merchant, Richard E Mains, Stephen M King, Betty A Eipper
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2017-05-01
Series:eLife
Subjects:
cilia
chlamdyomonas
planaria
amidation
golgi
peptidylglycine alpha-amidating monooxygenase
Online Access:https://elifesciences.org/articles/25728

Internet

https://elifesciences.org/articles/25728

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