A bioactive peptide amidating enzyme is required for ciliogenesis
The pathways controlling cilium biogenesis in different cell types have not been fully elucidated. We recently identified peptidylglycine α-amidating monooxygenase (PAM), an enzyme required for generating amidated bioactive signaling peptides, in Chlamydomonas and mammalian cilia. Here, we show that...
Main Authors: | Dhivya Kumar, Daniela Strenkert, Ramila S Patel-King, Michael T Leonard, Sabeeha S Merchant, Richard E Mains, Stephen M King, Betty A Eipper |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2017-05-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/25728 |
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