TLR7 agonist attenuates acetylcholine‐induced, Ca2+‐dependent ionic currents in swine tracheal submucosal gland cells

TLR7 agonist attenuates acetylcholine‐induced, Ca2+‐dependent ionic currents in swine tracheal submucosal gland cells

New Findings What is the central question of this study? Does Toll‐like receptor 7 (TLR7) have any direct effects on Ca2+‐dependent physiological function of tracheal submucosal gland cells? What is the main finding and its importance? TLR7 is co‐localized with SERCA2 in tracheal submucosal gland ce...

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Bibliographic Details
Main Authors: Shunichi Gamo, Tsutomu Tamada, Koji Murakami, Soshi Muramatsu, Hidemi Aritake, Masayuki Nara, Itsuro Kazama, Tatsuma Okazaki, Hisatoshi Sugiura, Masakazu Ichinose
Format: Article
Language:English
Published: Wiley 2018-11-01
Series:Experimental Physiology
Subjects:
CaCC
COPD
hypersecretion
R837
submucosal glands
Online Access:https://doi.org/10.1113/EP087221

Internet

https://doi.org/10.1113/EP087221

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