Role of Spinal Cord α2-Adrenoreceptors in Noradrenergic Inhibition of Nociceptive Transmission During Chemotherapy-Induced Peripheral Neuropathy

Role of Spinal Cord α2-Adrenoreceptors in Noradrenergic Inhibition of Nociceptive Transmission During Chemotherapy-Induced Peripheral Neuropathy

Chemotherapy-induced peripheral neuropathy (CIPN) is a problem during cancer treatment and for cancer survivors but the central mechanisms underlying CIPN remain understudied. This study aims to determine if CIPN is associated with alterations of noradrenergic modulation of nociceptive transmission...

Full description

Bibliographic Details
Main Authors: José Tiago Costa-Pereira, Joana Ribeiro, Isabel Martins, Isaura Tavares
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-01-01
Series:Frontiers in Neuroscience
Subjects:
descending pain modulation
antidepressants
paclitaxel
chemotherapy side-effects
cancer treatment
pain
Online Access:https://www.frontiersin.org/article/10.3389/fnins.2019.01413/full

Internet

https://www.frontiersin.org/article/10.3389/fnins.2019.01413/full

Similar Items