GPG-NH<sub>2 </sub>acts via the metabolite αHGA to target HIV-1 Env to the ER-associated protein degradation pathway

<p>Abstract</p> <p>Background</p> <p>The synthetic peptide glycyl-prolyl-glycine amide (GPG-NH<sub>2</sub>) was previously shown to abolish the ability of HIV-1 particles to fuse with the target cells, by reducing the content of the viral envelope glycoprote...

Full description

Bibliographic Details
Main Authors: Vahlne Anders, Höglund Stefan, Jejcic Alenka
Format: Article
Language:English
Published: BMC 2010-03-01
Series:Retrovirology
Online Access:http://www.retrovirology.com/content/7/1/20