Prevention of Shiga toxin 1-caused colon injury by plant-derived recombinant IgA

Prevention of Shiga toxin 1-caused colon injury by plant-derived recombinant IgA

Abstract Immunoglobulin A (IgA) is a candidate antibody for oral passive immunization against mucosal pathogens like Shiga toxin-producing Escherichia coli (STEC). We previously established a mouse IgG monoclonal antibody (mAb) neutralizing Shiga toxin 1 (Stx1), a bacterial toxin secreted by STEC. W...

Full description

Bibliographic Details
Main Authors: Katsuhiro Nakanishi, Taichi Takase, Yuya Ohira, Ryota Ida, Noriko Mogi, Yuki Kikuchi, Minami Matsuda, Kohta Kurohane, Yoshihiro Akimoto, Junri Hayakawa, Hayato Kawakami, Yasuo Niwa, Hirokazu Kobayashi, Eiji Umemoto, Yasuyuki Imai
Format: Article
Language:English
Published: Nature Portfolio 2022-10-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-22851-4

Internet

https://doi.org/10.1038/s41598-022-22851-4

Similar Items