A Comprehensive Analysis of Hungarian MODY Patients—Part I: Gene Panel Sequencing Reveals Pathogenic Mutations in <i>HNF1A</i>, <i>HNF1B</i>, <i>HNF4A</i>, <i>ABCC8</i> and <i>INS</i> Genes

A Comprehensive Analysis of Hungarian MODY Patients—Part I: Gene Panel Sequencing Reveals Pathogenic Mutations in <i>HNF1A</i>, <i>HNF1B</i>, <i>HNF4A</i>, <i>ABCC8</i> and <i>INS</i> Genes

Maturity-onset diabetes of the young (MODY) has about a dozen known causal genes to date, the most common ones being <i>HNF1A, HNF4A, HNF1B</i> and <i>GCK</i>. The phenotype of this clinically and genetically heterogeneous form of diabetes depends on the gene in which the pat...

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Bibliographic Details
Main Authors: Zsolt Gaál, Zsuzsanna Szűcs, Irén Kántor, Andrea Luczay, Péter Tóth-Heyn, Orsolya Benn, Enikő Felszeghy, Zsuzsanna Karádi, László Madar, István Balogh
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Life
Subjects:
MODY
monogenic diabetes
<i>HNF1A</i>
transcription factor MODY
next-generation sequencing
NGS
Online Access:https://www.mdpi.com/2075-1729/11/8/755

Internet

https://www.mdpi.com/2075-1729/11/8/755

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