Identification of metabolic pathways essential for fitness of Salmonella Typhimurium in vivo.

Bacterial infections remain a threat to human and animal health worldwide, and there is an urgent need to find novel targets for intervention. In the current study we used a computer model of the metabolic network of Salmonella enterica serovar Typhimurium and identified pairs of reactions (cut sets...

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Bibliographic Details
Main Authors: Lotte Jelsbak, Hassan Hartman, Casper Schroll, Jesper T Rosenkrantz, Sebastien Lemire, Inke Wallrodt, Line E Thomsen, Mark Poolman, Mogens Kilstrup, Peter R Jensen, John E Olsen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4081726?pdf=render