Design, synthesis and anti-diabetic activity of chromen-2-one derivatives

DPP-IV inhibitors have been immersed as promising pathway to treat Type 2 diabetes. Here we have reported designing of coumarin derivatives as DPP-IV inhibitors. Designed compounds have been studied for their binding with DPP-IV enzyme through molecular docking followed by synthesis. All synthesized...

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Bibliographic Details
Main Authors: Rina Soni, Sunil Dutt Durgapal, Shubhangi S. Soman, John J Georrge
Format: Article
Language:English
Published: Elsevier 2019-07-01
Series:Arabian Journal of Chemistry
Online Access:http://www.sciencedirect.com/science/article/pii/S1878535216302209