Synthesis, Anticancer Activity, and In Silico Studies of 5-(3-Bromophenyl)-<i>N</i>-aryl-4<i>H</i>-1,2,4-triazol-3-amine Analogs

Synthesis, Anticancer Activity, and In Silico Studies of 5-(3-Bromophenyl)-<i>N</i>-aryl-4<i>H</i>-1,2,4-triazol-3-amine Analogs

In the current study, we described the synthesis of ten new 5-(3-Bromophenyl)-<i>N</i>-aryl-4<i>H</i>-1,2,4-triazol-3-amine analogs (<b>4a–j</b>), as well as their characterization, anticancer activity, molecular docking studies, ADME, and toxicity prediction. The...

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Bibliographic Details
Main Authors: Mohamed Jawed Ahsan, Krishna Gautam, Amena Ali, Abuzer Ali, Abdulmalik Saleh Alfawaz Altamimi, Salahuddin, Manal A. Alossaimi, S. V. V. N. S. M. Lakshmi, Md. Faiyaz Ahsan
Format: Article
Language:English
Published: MDPI AG 2023-10-01
Series:Molecules
Subjects:
anticancer
ADME studies
cell lines
molecular docking
triazole
tubulin
Online Access:https://www.mdpi.com/1420-3049/28/19/6936

Internet

https://www.mdpi.com/1420-3049/28/19/6936

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