ACE2 and Furin Expressions in Oral Epithelial Cells Possibly Facilitate COVID-19 Infection via Respiratory and Fecal–Oral Routes

ACE2 and Furin Expressions in Oral Epithelial Cells Possibly Facilitate COVID-19 Infection via Respiratory and Fecal–Oral Routes

Background: Coronavirus disease 2019 (COVID-19) is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that mainly transfers from human to human via respiratory and gastrointestinal routes. The S-glycoprotein in the virus is the key factor for the entry of SARS-CoV-2 into the cell...

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Bibliographic Details
Main Authors: Mei Zhong, Bingpeng Lin, Janak L. Pathak, Hongbin Gao, Andrew J. Young, Xinhong Wang, Chang Liu, Kaibin Wu, Mingxiao Liu, Jian-ming Chen, Jiangyong Huang, Learn-Han Lee, Cui-ling Qi, Linhu Ge, Lijing Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-12-01
Series:Frontiers in Medicine
Subjects:
COVID-19
SARS-CoV-2
ACE2 (angiotensin converting enzyme-2)
Furin
oral mucosa
single cell RNA seq
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2020.580796/full

Internet

https://www.frontiersin.org/articles/10.3389/fmed.2020.580796/full

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