Anti-allergic role of cholinergic neuronal pathway via α7 nicotinic ACh receptors on mucosal mast cells in a murine food allergy model.

The prevalence of food allergy (FA) has increased in developed countries over the past few decades. However, no effective drug therapies are currently available. Therefore, we investigated cholinergic anti-inflammatory pathway as a regulatory system to ameliorate disrupted mucosal immune homeostasis...

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Bibliographic Details
Main Authors: Takeshi Yamamoto, Toshihisa Kodama, Jaemin Lee, Naho Utsunomiya, Shusaku Hayashi, Hiroshi Sakamoto, Hirofumi Kuramoto, Makoto Kadowaki
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3894205?pdf=render