HDAC inhibitors as antifibrotic drugs in cardiac and pulmonary fibrosis

Fibrosis usually results from dysregulated wound repair and is characterized by excessive scar tissue. It is a complex process with unclear mechanisms. Accumulating evidence indicates that epigenetic alterations, including histone acetylation, play a pivotal role in this process. Histone acetylation...

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Bibliographic Details
Main Authors: Xing Lyu, Min Hu, Jieting Peng, Xiangyu Zhang, Yan Y Sanders
Format: Article
Language:English
Published: SAGE Publishing 2019-07-01
Series:Therapeutic Advances in Chronic Disease
Online Access:https://doi.org/10.1177/2040622319862697