TRPM4 regulates hilar mossy cell loss in temporal lobe epilepsy
Abstract Background Mossy cells comprise a large fraction of excitatory neurons in the hippocampal dentate gyrus, and their loss is one of the major hallmarks of temporal lobe epilepsy (TLE). The vulnerability of mossy cells in TLE is well known in animal models as well as in patients; however, the...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2023-04-01
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Series: | BMC Biology |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12915-023-01604-3 |