Epigallocatechin 3-Gallate Has a Neuroprotective Effect in Retinas of Rabbits with Ischemia/Reperfusion through the Activation of Nrf2/HO-1

Epigallocatechin 3-Gallate Has a Neuroprotective Effect in Retinas of Rabbits with Ischemia/Reperfusion through the Activation of Nrf2/HO-1

Retinal ischemia-reperfusion (rI/R) generates an oxidative condition causing the death of neuronal cells. Epigallocatechin 3-gallate (EGCG) has antioxidant and anti-inflammatory properties. Nonetheless, its correlation with the pathway of nuclear factor erythroid 2-related factor 2/heme oxygenase-1...

Full description

Bibliographic Details
Main Authors: Josué Rivera-Pérez, Martín Martínez-Rosas, César A. Conde-Castañón, Julia D. Toscano-Garibay, Nancy J. Ruiz-Pérez, Pedro L. Flores, Elvia Mera Jiménez, Javier Flores-Estrada
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:International Journal of Molecular Sciences
Subjects:
retinal ischemia/reperfusion (rI/R)
epigallocatechin-3-gallate (EGCG)
high-mobility group Box 1 (HMGB1)
nuclear factor erythroid 2-related factor 2 (Nrf2)
heme oxygenase-1 (HO-1)
Online Access:https://www.mdpi.com/1422-0067/21/10/3716

Internet

https://www.mdpi.com/1422-0067/21/10/3716

Similar Items