Disorder‐to‐order transition in PE–PPE proteins of Mycobacterium tuberculosis augments the pro‐pathogen immune response

Disorder‐to‐order transition in PE–PPE proteins of Mycobacterium tuberculosis augments the pro‐pathogen immune response

A growing body of evidence supports the hypothesis that intrinsically disordered proteins often mediate host–pathogen interactions and modulate host functions for pathogen survival and virulence. Mycobacterium tuberculosis (M.tb) has evolved largely through reductive evolution, with a few exceptions...

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Bibliographic Details
Main Authors: Javeed Ahmad, Mohd Khubaib, Javaid Ahmad Sheikh, Rita Pancsa, Saroj Kumar, Alagiri Srinivasan, Mohan Madan Babu, Seyed E. Hasnain, Nasreen Z. Ehtesham
Format: Article
Language:English
Published: Wiley 2020-01-01
Series:FEBS Open Bio
Subjects:
folding‐upon‐binding
immune modulation
immunogenicity
Mycobacterium tuberculosis
pathogenesis
protein–protein interaction
Online Access:https://doi.org/10.1002/2211-5463.12749

Internet

https://doi.org/10.1002/2211-5463.12749

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