G4Beacon: An In Vivo G4 Prediction Method Using Chromatin and Sequence Information

G-quadruplex (G4) structures are critical epigenetic regulatory elements, which usually form in guanine-rich regions in DNA. However, predicting the formation of G4 structures within living cells remains a challenge. Here, we present an ultra-robust machine learning method, G4Beacon, which utilizes...

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Bibliographic Details
Main Authors: Zhuofan Zhang, Rongxin Zhang, Ke Xiao, Xiao Sun
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Biomolecules
Subjects:
Online Access:https://www.mdpi.com/2218-273X/13/2/292