An integrative approach to assessing effects of a short-term Western diet on gene expression in rat liver

An integrative approach to assessing effects of a short-term Western diet on gene expression in rat liver

Consumption of a diet rich in saturated fatty acids and carbohydrates contributes to the accumulation of fat in the liver and development of non-alcoholic steatohepatitis (NASH). Herein we investigated the hypothesis that short-term consumption of a high fat/sucrose Western diet (WD) alters the geno...

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Bibliographic Details
Main Authors: Jaclyn E. Welles, Holly Lacko, Yuka Imamura Kawasawa, Michael D. Dennis, Leonard S. Jefferson, Scot R. Kimball
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Endocrinology
Subjects:
diet-induced obesity
nonalcoholic fatty liver disease (NAFLD)
mRNA translation
mTORC1
gene regulation
liver
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2022.1032293/full

Internet

https://www.frontiersin.org/articles/10.3389/fendo.2022.1032293/full

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