Rapamycin reverses ferroptosis by increasing autophagy in MPTP/MPP+-induced models of Parkinson’s disease

Rapamycin reverses ferroptosis by increasing autophagy in MPTP/MPP+-induced models of Parkinson’s disease

Parkinson’s disease is a neurodegenerative disorder, and ferroptosis plays a significant role in the pathological mechanism underlying Parkinson’s disease. Rapamycin, an autophagy inducer, has been shown to have neuroprotective effects in Parkinson’s disease. However, the link between rapamycin and...

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Bibliographic Details
Main Authors: Tongyu Liu, Peihan Wang, Huan Yin, Xiangfei Wang, Jing Lv, Jiang Yuan, Jing Zhu, Yunfu Wang
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2023-01-01
Series:Neural Regeneration Research
Subjects:
autophagy; behavior; ferroptosis; mptp; parkinson’s disease; pc12 cell; rapamycin; tyrosine hydroxylase
Online Access:http://www.nrronline.org/article.asp?issn=1673-5374;year=2023;volume=18;issue=11;spage=2514;epage=2519;aulast=Liu

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http://www.nrronline.org/article.asp?issn=1673-5374;year=2023;volume=18;issue=11;spage=2514;epage=2519;aulast=Liu

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