Selective PPAR-Delta/PPAR-Gamma Activation Improves Cognition in a Model of Alzheimer’s Disease

Selective PPAR-Delta/PPAR-Gamma Activation Improves Cognition in a Model of Alzheimer’s Disease

<i>Background:</i> The continuously increasing association of Alzheimer’s disease (AD) with increased mortality rates indicates an unmet medical need and the critical need for establishing novel molecular targets for therapeutic potential. Agonists for peroxisomal proliferator activating...

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Bibliographic Details
Main Authors: Ian Steinke, Manoj Govindarajulu, Priyanka Das Pinky, Jenna Bloemer, Sieun Yoo, Tracey Ward, Taylor Schaedig, Taylor Young, Fajar Setyo Wibowo, Vishnu Suppiramaniam, Rajesh H. Amin
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:Cells
Subjects:
peroxisomal proliferator activating receptor
in silico drug design
neurodegeneration
Alzheimer’s disease
synaptic plasticity
behavioral deficits
Online Access:https://www.mdpi.com/2073-4409/12/8/1116

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https://www.mdpi.com/2073-4409/12/8/1116

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