Phosphorylation of Tyrosine 841 Plays a Significant Role in JAK3 Activation

Phosphorylation of Tyrosine 841 Plays a Significant Role in JAK3 Activation

Janus Kinase 3 (JAK3) plays a key role in the development, proliferation, and differentiation of various immune cells. It regulates gene expression by phosphorylation of Signal Transducers and Activators of Transcriptions (STATs) via the JAK/STAT pathway. Recently, we found a new JAK3 phosphorylatio...

Full description

Bibliographic Details
Main Authors: Shengjie Sun, Georgialina Rodriguez, Yixin Xie, Wenhan Guo, Alan E. Lopez Hernandez, Jason E. Sanchez, Robert Arthur Kirken, Lin Li
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:Life
Subjects:
JAK3
phosphorylation
tyrosine
Delphi
electrostatic potential
MMPBSA
Online Access:https://www.mdpi.com/2075-1729/13/4/981

Internet

https://www.mdpi.com/2075-1729/13/4/981

Similar Items