Ketogenic diet therapy for pediatric epilepsy is associated with alterations in the human gut microbiome that confer seizure resistance in mice

Ketogenic diet therapy for pediatric epilepsy is associated with alterations in the human gut microbiome that confer seizure resistance in mice

Summary: The gut microbiome modulates seizure susceptibility and the anti-seizure effects of the ketogenic diet (KD) in animal models, but whether these relationships translate to KD therapies for human epilepsy is unclear. We find that the clinical KD alters gut microbial function in children with...

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Bibliographic Details
Main Authors: Gregory R. Lum, Sung Min Ha, Christine A. Olson, Montgomery Blencowe, Jorge Paramo, Beck Reyes, Joyce H. Matsumoto, Xia Yang, Elaine Y. Hsiao
Format: Article
Language:English
Published: Elsevier 2023-12-01
Series:Cell Reports
Subjects:
CP: Microbiology
CP: Neuroscience
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124723015334

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http://www.sciencedirect.com/science/article/pii/S2211124723015334

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