Prognostic Impact of HER2 and ER Status of Circulating Tumor Cells in Metastatic Breast Cancer Patients with a HER2-Negative Primary Tumor

Prognostic Impact of HER2 and ER Status of Circulating Tumor Cells in Metastatic Breast Cancer Patients with a HER2-Negative Primary Tumor

BACKGROUND: Preclinical and clinical studies have reported that human epidermal growth factor receptor 2 (HER2) overexpression yields resistance to endocrine therapies. Here the prevalence and prognostic impact of HER2-positive circulating tumor cells (CTCs) were investigated retrospectively in meta...

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Bibliographic Details
Main Authors: Nick Beije, Wendy Onstenk, Jaco Kraan, Anieta M. Sieuwerts, Paul Hamberg, Luc Y. Dirix, Anja Brouwer, Felix E. de Jongh, Agnes Jager, Caroline M. Seynaeve, Ngoc M. Van, John A. Foekens, John W.M. Martens, Stefan Sleijfer
Format: Article
Language:English
Published: Elsevier 2016-11-01
Series:Neoplasia: An International Journal for Oncology Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558616301336

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http://www.sciencedirect.com/science/article/pii/S1476558616301336

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