Enhanced Intestinal Permeability of Cefixime by Self-Emulsifying Drug Delivery System: In-Vitro and Ex-Vivo Characterization

Enhanced Intestinal Permeability of Cefixime by Self-Emulsifying Drug Delivery System: In-Vitro and Ex-Vivo Characterization

Background: Cefixime (CFX) belongs to a group of third-generation cephalosporin antibiotics with low water solubility and low intestinal permeability, which ultimately leads to significantly low bioavailability. Aim: This study aimed to increase solubility, improve drug release, and intestinal perme...

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Bibliographic Details
Main Authors: Arshad Mahmood, Laraib Khan, Muhammad Ijaz, Imran Nazir, Mahrukh Naseem, Muhammad Azam Tahir, Muhammad Naeem Aamir, Masood Ur Rehman, Mulazim Hussain Asim
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:Molecules
Subjects:
oral bioavailability
cefixime
self-nanoemulsifying drug delivery system (SEDDS)
permeation enhancement
Online Access:https://www.mdpi.com/1420-3049/28/6/2827

Internet

https://www.mdpi.com/1420-3049/28/6/2827

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