Granulocyte macrophage colony-stimulating factor enhances the modulatory effect of cytokines on monocyte-derived multinucleated giant cell formation and fungicidal activity against Paracoccidioides brasiliensis

Multinucleated giant cells (MGC) are cells present in characteristic granulomatous inflammation induced by intracellular infectious agents or foreign materials. The present study evaluated the modulatory effect of granulocyte macrophage colony-stimulating factor (GM-CSF) in association with other cy...

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Bibliographic Details
Main Authors: Magda Paula Pereira do Nascimento, Camila Ferreira Bannwart, Erika Nakaira-Takahagi, Maria Terezinha Serrão Peraçoli
Format: Article
Language:English
Published: Fundação Oswaldo Cruz (FIOCRUZ) 2011-09-01
Series:Memorias do Instituto Oswaldo Cruz
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762011000600014&lng=en&tlng=en