Elucidation of disease etiology by trans-layer omics analysis

Abstract To date, genome-wide association studies (GWASs) have successfully identified thousands of associations between genetic polymorphisms and human traits. However, the pathways between the associated genotype and phenotype are often poorly understood. The transcriptome, proteome, and metabolom...

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Bibliographic Details
Main Authors: Yuya Shirai, Yukinori Okada
Format: Article
Language:English
Published: BMC 2021-02-01
Series:Inflammation and Regeneration
Online Access:https://doi.org/10.1186/s41232-021-00155-w