CD4+ T cells are the major predictor of HCMV control in allogeneic stem cell transplant recipients on letermovir prophylaxis

CD4+ T cells are the major predictor of HCMV control in allogeneic stem cell transplant recipients on letermovir prophylaxis

IntroductionHuman cytomegalovirus (HCMV) causes significant morbidity and mortality in allogeneic stem cell transplant (alloSCT) recipients. Recently, antiviral letermovir prophylaxis during the first 100 days after alloSCT replaced PCR-guided preemptive therapy as the primary standard of care for H...

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Bibliographic Details
Main Authors: Chris David Lauruschkat, Ihsan Muchsin, Alice Rein, Florian Erhard, Denise Grathwohl, Lars Dölken, Carolin Köchel, Christine Susanne Falk, Hermann Einsele, Sebastian Wurster, Götz Ulrich Grigoleit, Sabrina Kraus
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-05-01
Series:Frontiers in Immunology
Subjects:
human cytomegalovirus (HCMV)
viral infection
allogeneic stem cell transplantation
T cells
NK cells
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1148841/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2023.1148841/full

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