Efficient Editing of Malaria Parasite Genome Using the CRISPR/Cas9 System
ABSTRACT Malaria parasites are unicellular organisms residing inside the red blood cells, and current methods for editing the parasite genes have been inefficient. The CRISPR/Cas9 (clustered regularly interspaced short palindromic repeats and Cas9 endonuclease-mediated genome editing) system is a ne...
Main Authors: | , , , , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
American Society for Microbiology
2014-08-01
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Series: | mBio |
Online Access: | https://journals.asm.org/doi/10.1128/mBio.01414-14 |