Next-Generation Sequencing Revealed a Distinct Immunoglobulin Repertoire with Specific Mutation Hotspots in Acute Myeloid Leukemia
Immunoglobulin (Ig) is known as a hallmark of B-lymphocytes exerting antibody functions. However, our previous studies demonstrated that myeloblasts from acute myeloid leukemia (AML) patients could also express Ig with distinct roles. Here, we quantified Ig (IGHG and IGK) transcripts by real-time PC...
Auteurs principaux: | , , , , , , , , , , |
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Format: | Article |
Langue: | English |
Publié: |
MDPI AG
2022-01-01
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Collection: | Biology |
Sujets: | |
Accès en ligne: | https://www.mdpi.com/2079-7737/11/2/161 |