Perinatal exposure to the fungicide ketoconazole alters hypothalamic control of puberty in female rats

Perinatal exposure to the fungicide ketoconazole alters hypothalamic control of puberty in female rats

IntroductionEstrogenic endocrine disrupting chemicals (EDCs) such as diethylstilbestrol (DES) are known to alter the timing of puberty onset and reproductive function in females. Accumulating evidence suggests that steroid synthesis inhibitors such as ketoconazole (KTZ) or phthalates may also affect...

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Bibliographic Details
Main Authors: Delphine Franssen, Hanna K. L. Johansson, David Lopez-Rodriguez, Arnaud Lavergne, Quentin Terwagne, Julie Boberg, Sofie Christiansen, Terje Svingen, Anne-Simone Parent
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-04-01
Series:Frontiers in Endocrinology
Subjects:
endocrine disrupting chemicals (EDCs)
hypothalamus
puberty
transcriptome
reproduction
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2023.1140886/full

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https://www.frontiersin.org/articles/10.3389/fendo.2023.1140886/full

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