Transport and Secretion of the Wnt3 Ligand by Motor Neuron-like Cells and Developing Motor Neurons

The vertebrate neuromuscular junction (NMJ) is formed by a presynaptic motor nerve terminal and a postsynaptic muscle specialization. Cumulative evidence reveals that Wnt ligands secreted by the nerve terminal control crucial steps of NMJ synaptogenesis. For instance, the Wnt3 ligand is expressed by...

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Bibliographic Details
Main Authors: Cristina Pinto, Viviana Pérez, Jessica Mella, Miguel Albistur, Teresa Caprile, Francisca C. Bronfman, Juan Pablo Henríquez
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Biomolecules
Subjects:
Online Access:https://www.mdpi.com/2218-273X/11/12/1898